NFL injury news, with the betting lens.

Who’s out, who’s questionable, and which lines it touches, filtered from the wire around the clock. When a key name drops, Big Mike texts the adjusted play before the number moves.

1. NFL49ers rule veteran WR Mike Evans out after rib injuryThe 49ers lost veteran WR Mike Evans in the first half of Sunday's game against the Cardinals due to a rib injury.ESPN NFL · 6:10 PM ET · Sep 27
2. NFLNFL Week 3: Takeaways, questions, fantasy spin for Sunday's gamesOur NFL Nation reporters react to all the action, answering the biggest questions coming out of each Sunday game. Here's what we learned from Week 3.ESPN NFL · 5:45 PM ET · Sep 27
3. NFLNFL Week 3: Takeaways, questions, fantasy spin for Sunday gamesOur NFL Nation reporters react to all the action, answering the biggest questions coming out of each Sunday game. Here's what we learned from Week 3.5:11 PM ET · Sep 27
4. NFLBuccaneers WR Jalen McMillan suffers knee injury vs. VikingsBuccaneers wide receiver Jalen McMillan suffered a knee injury in the first quarter against the Vikings and has been ruled out.5:08 PM ET · Sep 27
5. NFLBuccaneers WR Jalen McMillan suffers knee injury vs. VikingsBuccaneers wide receiver Jalen McMillan suffered a knee injury in the first quarter against the Vikings and has been ruled out.ESPN NFL · 5:05 PM ET · Sep 27
6. NFLColts end 9-game skid with 19-17 victory over Texans as Shrader kicks winner with 16 seconds left— Spencer Shrader fought through a groin injury to make four field goals, including a 43-yarder with 16 seconds to go, and the Indianapolis Colts'...4:49 PM ET · Sep 27
7. NFLNFL Week 3: Takeaways, questions, fantasy spin for Sunday gamesOur NFL Nation reporters react to all the action, answering the biggest questions coming out of each Sunday game. Here's what we learned from Week 2.ESPN NFL · 4:30 PM ET · Sep 27 · Big Mike’s read →
8. NFLDolphins RB De'Von Achane suffers knee injury vs. ChiefsDolphins running back De'Von Achane suffered a knee injury in Sunday's game against the Chiefs.ESPN NFL · 2:59 PM ET · Sep 27 · Big Mike’s read →
9. NFLDolphins RB De'Von Achane suffers knee injury vs. ChiefsDolphins running back De'Von Achane suffered a knee injury in Sunday's game against the Chiefs.ESPN NFL · 2:59 PM ET · Sep 27 · Big Mike’s read →
10. NFLDolphins RB De'Von Achane suffers knee injury vs. ChiefsDolphins running back De'Von Achane suffered a knee injury in Sunday's game against the Chiefs.ESPN NFL · 2:59 PM ET · Sep 27 · Big Mike’s read →
11. NFLCommanders LB Leo Chenal injured making tackle, carted offCommanders linebacker Leo Chenal was carted off the field with a neck injury after making a tackle late in the second quarter against the Seahawks.ESPN NFL · 2:43 PM ET · Sep 27 · Big Mike’s read →
12. NFLCommanders LB Leo Chenal injured making tackle, carted offCommanders linebacker Leo Chenal was carted off the field with a neck injury after making a tackle late in the second quarter against the Seahawks.ESPN NFL · 2:43 PM ET · Sep 27
13. NFLBears QB Bagent clears protocol; Keenum likely to start vs. EaglesThe Bears' Tyson Bagent has cleared the concussion protocol, but Case Keenum is expected to start Monday night's game at QB against the Eagles.ESPN NFL · 2:40 PM ET · Sep 27 · Big Mike’s read →
14. NFLJets without WR Adonai Mitchell (finger) vs. LionsJets wide receiver Adonai Mitchell is inactive Sunday because of a finger injury.ESPN NFL · 11:40 AM ET · Sep 27
15. NFLSources: Caleb Williams injury considered to have 3-4 week timelineBears quarterback Caleb Williams has a Grade 2 hamstring injury that doctors say could sideline him for three to four weeks, league sources told ESPN and NFL Network.9:53 AM ET · Sep 27 · Big Mike’s read →
16. NFLSources: Caleb Williams injury considered to have 3-4 week timelineBears QB Caleb Williams has a Grade 2 hamstring injury that doctors consider a three-to-four-week injury, league sources told ESPN and NFL Network.ESPN NFL · 8:00 AM ET · Sep 27
17. NFLSources: Caleb Williams injury considered to have 3-4 week timelineBears QB Caleb Williams has a Grade 2 hamstring injury that doctors say could sideline him for three to four weeks, league sources told ESPN and NFL Network.ESPN NFL · 8:00 AM ET · Sep 27
18. NFLNFL Week 3 Trends Reshape Teams and Fantasy StrategiesKey StoriesQuarterback battles intensify as injuries and draft prospects reshape rostersThe Falcons' quarterback competition heats up with Michael Penix Jr.'s return, potentially sidelining Tua Tagovailoa, while Ole Miss standout Trinidad Chambliss emerges as a top 2027 NFL Draft prospect. Jaxson Dart's season-ending injury leaves the Giants reliant on Jameis Winston, suggesting a shift in scouting priorities for college-to-pro transitions.Injuries force roster adjustments and depth signings across NFLTeams are addressing injuries by signing veteran players, such as the Chargers adding Marquez Valdes-Scantling and the 49ers acquiring Naquan Jones. The Rams are cautiously managing Puka Nacua's groin injury, while the Giants face mixed news on Andrew Thomas and Brian Burns.Fantasy football managers face critical start-or-sit decisions for Week 3Drake Maye and Trevor Lawrence are both top-10 quarterback options, but fantasy managers must choose between them for Week 3. DefNFL News · 7:04 AM ET · Sep 27
19. NFLNFL Rosters Shift Amid Surging Injury CrisisKey StoriesRams Star Myles Garrett Sidelined After Knee Surgery — Defensive standout Myles Garrett is expected to miss approximately six weeks following knee surgery, with the team taking a cautious approach to his recovery timeline.Caleb Williams Ruled Out for Monday Night Football — The Bears will be without rookie quarterback Caleb Williams for their clash against the Eagles, leading to Tyson Bagent returning to practice as the starter.Injury-Depleted 49ers Search for Defensive Line Help — Following the loss of six defensive linemen in a two-week span, San Francisco is working out veterans including Matt Judon and Jamin Davis to bolster their front.Eagles Get Boost with Barkley and Smith Clearance — Philadelphia received positive injury news as Saquon Barkley and DeVonta Smith were removed from the injury report ahead of their Monday night game.Broncos Place Jonah Coleman on Injured Reserve — Running back Jonah Coleman will miss at least four games withAdam Schefter · 7:02 AM ET · Sep 27
20. NFLSources: Myles Garrett faces 6-week timeline from knee surgeryMyles Garrett was given a six-week recovery timeline from his knee surgery, meaning the star pass rusher might not return until early November, sources told NFL Network.ESPN NFL · 6:35 AM ET · Sep 27
21. NFL“Caitlin Clark Deserves So Much Better”: NFL Insider Calls Out ESPN Veteran’s Reporing on the Fever StarEven after being a host for ESPN for 34 years, Linda Cohn’s is being called out for her opinions on women’s basketball. Her outspoken commentary around Caitlin Clark has recently drawn the attention of NFL insider James Boyd, who believes what Cohn does not do justice to reporting, as the Indiana Fever star and her team prepare to play the Las Vegas Aces.ESPN NFL · 12:57 AM ET · Sep 27
22. NFLBroncos place RB Jonah Coleman (ankle) on IRDenver Broncos rookie running back Jonah Coleman was placed on injured reserve Saturday with an ankle he injury he suffered in the team's Week 2 win over the Jacksonville Jaguars.ESPN NFL · 6:24 PM ET · Sep 26 · Big Mike’s read →